The Wüstebach catchment, which is part of the German TERENO (Terrestrial Environmental Observatories) network, was partially deforested in 2013 to promote natural forest regrowth. This data paper provides 16 years of hourly concentrations and fluxes of 11 solutes and runoff rates (2010–2024) from two runoff gauging stations, one affected by deforestation and one not, illustrating forest-management effects on solute transport processes at the catchment scale.