This study presents long-term (i.e., 1940–2022) and high-resolution (i.e., 0.25°) monthly time series of TWS anomalies over the global land surface. The reconstruction is achieved by using a set of machine learning models with a large number of predictors, including climatic and hydrological variables, land use/land cover data, and vegetation indicators (e.g., leaf area index). Our proposed GTWS-MLrec performs overall as well as, or is more reliable than, previous TWS datasets.