We present a dataset of annual glacier mass changes for all the 661 glaciers in the French Alps for the 1967–2015 period, reconstructed using deep learning (i.e. artificial intelligence). We estimate an average annual mass loss of –0.69 ± 0.21 m w.e., the highest being in the Chablais, Ubaye and Champsaur massifs and the lowest in the Mont Blanc, Oisans and Haute Tarentaise ranges. This dataset can be of interest to hydrology and ecology studies on glacierized catchments in the French Alps.