<p>Due to the many factors controlling δ<sup>13</sup>C values in stalagmites, complicating their paleoclimatic and paleoenvironmental interpretation, most studies do not present δ<sup>13</sup>C values, but instead focus mainly on δ18O values. This is also the case for most cave studies from tropical South America, where many new δ18O stalagmite records covering the last millennia were recently published. Here, we test the influence of local hydroclimate, altitude, temperature and changing vegetation types on δ<sup>13</sup>C values in stalagmites, by employing a new dataset (named δ<sup>13</sup>C_2k_SA, <a href="https://doi.pangaea.de/10.1594/PANGAEA.919050"target="_blank">https://doi.pangaea.de/10.1594/PANGAEA.919050</a>) composed of published and unpublished carbon isotope records from various sites in tropical South America. Most locations were dominated by C<sub>3</sub> plants over the last two millennia and are characterized by speleothem δ<sup>13</sup>C values more depleted than −6 ‰. The main factors influencing δ<sup>13</sup>C values are associated with the local hydroclimate, followed by minor effects from temperature. Most of the isotopic records show a significant correlation between the δ<sup>13</sup>C and δ18O values, indicating a close relationship between local hydroclimate and atmospheric convective processes related to the South American Monsoon System.</p>